C5AR1 anticorps (PE)
Aperçu rapide pour C5AR1 anticorps (PE) (ABIN306244)
Antigène
Voir toutes C5AR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes murine CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 Molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Clone 20/70 has been reported to block the binding of the C5a to murine CD88. XXX recommend the use of MCA2457EL for this purpose.
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Purification
- Protein G purified
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Immunogène
- RBL-2H3 transfected cells expressing murine C5aR.
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Isotype
- IgG2b
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Indications d'application
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Approved: Flo (1:1 - 1:10)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Distilled Water.
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Concentration
- Lot specific
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Buffer
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Store undiluted.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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Autre désignation
- C5AR1 / CD88 / C5a Receptor
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Sujet
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Name/Gene ID: C5AR1
Subfamily: Anaphylatoxin
Family: GPCR
Synonyms: C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen -
ID gène
- 728
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Pathways
- Système du Complément
Antigène
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